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In a randomized, double-blind, placebo-controlled trial, daily supplementation with Lactobacillus plantarum ECGC 13110402 for 12 weeks in adults with moderate hypercholesterolemia resulted in a significant reduction in LDL cholesterol and hs-CRP compared to placebo, suggesting a direct benefit of probiotics on cardiovascular risk markers in humans (Costabile et al., 2017)

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During the de novo synthesis of purine nucleotides, many reactions require a great deal of energy utilizing the hydrolysis of adenosine triphosphate (ATP)

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[PMC free article: PMC4852176] [PubMed: 27199894] 204