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Cell-penetrating peptide conjugates of steric blocking oligonucleotides as therapeutics for neuromuscular diseases from a historical perspective to current prospects of treatment

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Base-catalyzed click reactions between alkynes and 2-bromo-4- tert -butylazidobenzene or between azides and 2-bromo-4- tert -butylphenylacetylene produced 1,5-diaryl-1,2,3-triazoles