Lilly's phase 2 results published in the New England Journal of Medicine show orforglipron achieved up to 14.7% mean weight reduction [press release]
As we get older, our body's ability to make this important substance slowly decreases
That requires large controlled trials and regulatory review
Comment: We received support from commenters for a variety of existing and proposed complexity adjustments
They include, but are not limited to: anxiety, double or blurry vision, racing heart, confusion, dizziness, moodiness and mood swings, irritability, nervousness, flushing, tremors, sweet cravings, rhinitis, panic attacks, numbness and cold in extremities, confusion, irrationality, hot flashes, bad temper, mood swings, trouble talking, disorientation, hangriness, the need to sleep or crashing, insomnia, headache, fatigue, hunger, light-headedness, sweating, poor concentration, shakiness, trouble sleeping, feeling wired, feeling faint, extreme tiredness, weakness, paleness, mouth tingling, heart palpitations, and nausea
Saline (0.9% NaCl): While sterile, the salt content can sometimes cause certain complex peptides to clump or degrade faster
