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Sturniolo GC, Molokhia MM, Shields R, Turnberg LA
The work was funded with grants from ISCIIIs Fund for Research in Health Sciences and the Community of Madrid
Compound 968 can inhibit the activity of GLS2 and overcome the resistance of cancer cells to selective GLS1 inhibitors, resulting in tumor suppression (Lukey et al., 2019)
[DOI] [PubMed] [Google Scholar] 113.Mofarrahi M., Brandes R.P., Gorlach A., Hanze J., Terada L.S., Quinn M.T., Mayaki D., Petrof B., Hussain S.N.A
The most remarkable instance is in selenoprotein F (SELENOF), an ER protein involved in glycoprotein folding quality control