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in preclinical models it activates the VEGFR2-Akt-eNOS signaling axis to promote angiogenesis and tissue vascularization ( It also engages ERK1/2 and FAK-paxillin pathways that regulate endothelial cell migration and fibroblast activity, and upregulates heat shock proteins (HSP70/90) for cytoprotective effects in gastrointestinal tissue models ( Research across multiple rodent injury models has characterized its activity in tendon, muscle, nerve, and GI tissue contexts

Proinflammatory cytokines stimulate the expression of nerve growth factor by human intervertebral disc cells

There's no required testing for purity, potency, sterility, or endotoxins

2019 May 31;24(11):2076

In the brain it acts as an excitatory neuromodulator, which essentially means that it facilitates greater availability of dopamine

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