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Nature 264, 247249

10.1016/j.clnu.2022.07.040 Clin Nutr

Glp1r is also detected in Paneth cells, identified by lysozyme expression, in the jejunum and ileum crypts but not colon, distinct from proliferating Ki67+ cells (Kedees et al., 2013)

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The medication affects the hunger control centre of the brain to decrease hunger, slow gastric emptying, and increase the feeling of fullness after meals, which leads to reduced caloric intake and weight loss