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Skin purging is a phenomenon that some people with breakout-prone skin experience after using a leave-on exfoliant or certain other active ingredients for the first time

However, like all medications, they can cause side effects such as nausea, vomiting, constipation and diarrhea

doi: 10.1016/j.canlet.2012.06.007

Worth adding a variable nobody measured: chronodisruption

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These include if you are pregnant or breastfeeding, have a disease that affects your intestines and how well you digest your foods, or if you have a strict diet that doesnt give you enough vitamins