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Indeed, many labs have measured high levels of GHSR1a mRNA in the arcuate nucleus (Howard et al., 1996

According to the FDA-approved prescribing information, headache is listed as a recognized adverse reaction for semaglutide products including Ozempic (for type 2 diabetes), Wegovy (for weight management), and Rybelsus (oral semaglutide)

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While the data is reassuring and it seems like Ozempic may slow the progression of CKD in people with Type 2 diabetes, more significant, long-term studies are needed to understand if and how Ozempic could help manage kidney disease

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