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Key compounds: BPC-157 (15-amino-acid peptide from gastric protective protein

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The TRIUMPH-4 Phase 3 trial in obesity with knee osteoarthritis (Bays et al., NEJM 2025) reported 28.7% mean weight loss at 68 weeks at the 12 mg dose, plus a 75.8% reduction in WOMAC knee pain scores

Epidemiological studies support that Hispanics, Blacks, females, and those with lower socioeconomic status have higher obesity prevalence rates