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von Herrath M, Bain SC, Bode B et al (2021) Anti-interleukin-21 antibody and liraglutide for the preservation of -cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial

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NICE (CG189) additionally recommends framing goals in terms of overall outcomes for example, a 510% reduction in body weight over three to six months within a multi-component programme which can be more motivating and clinically meaningful than focusing solely on weekly targets

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GI effects are the primary concern, primarily nausea, vomiting, diarrhea, and constipation

How To Use Semaglutide Patients typically use semaglutide as a once-weekly injection