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Although the nanoparticle drug delivery system was not initially designed for LDL-receptor-mediated brain targeting, it was later found that apolipoprotein E would be absorbed on the polysorbate 80 coated nanoparticles upon incubation of the nanoparticles with human plasma resulting in LDL-receptor mediated BBB crossing

Song M, Xiong J, Wang Y et al (2012) VIP enhances phagocytosis of fibrillar beta-amyloid by microglia and attenuates amyloid deposition in the brain of APP/PS1 mice

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Certificate of Analysis DSIP 10mg COA Number 2607100571 Lot PH-dp10-0322 Reported 07/13/2026 Certificate of Analysis DSIP 10mg COA Number 2605280410 Lot PH-dp101115 Reported 05/30/2026 Certificate of Analysis DSIP 10mg COA Number 2603230050 Lot PH-dp101115 Reported 03/24/2026 Certificate of Analysis DSIP 5mg COA Number 2512050190 Lot N/A Reported 12/08/2025 DSIP Specifications DSIP Chemical Structure Legal Disclaimer: DSIP is sold by Protide Health for laboratory research purposes only

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