glp 1 antidepressant Microbiota modulates the effects of GLP-1 analogues Insights into a possible role

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J Cell Mol Med (2021) 25(23):10798813

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Discussion Although histamine is elevated in the mucosa of active UC, and urinary histamine metabolites correlate with disease activity, 22, 32 the mechanistic consequences of histamine release and receptor activation is lacking, limiting its consideration as a therapeutic target