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Mitochondrial superoxide production is related to the control of cytokine release from peritoneal macrophage after antioxidant treatment in septic rats

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described 12 patients with a mean follow-up of 4.8 years (range, 1.310.2 years), of whom half remained disease-free, while others developed recurrence or died of disease (38)

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However, when cancer has developed, the death of malignant cells by treatment with chemotherapeutic drugs and radiation that produce free radicals in the cells, such as hydrogen peroxide and superoxide, mostly depends on their oxidative damage (8)

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