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Weight regain after GLP-1 therapy has become a growing concern as more patients discontinue treatments like semaglutide or liraglutide

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The study also showed a substantial connection between DPP-IV, immune cell infiltration, immune response, and 21 immune checkpoint genes (ICGs) in THCA

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There are three main biotransformation pathways (see Figure 2) involved in methamphetamine metabolic clearance: (1) N-demethylation to produce amphetamine, (2) aromatic hydroxylation producing 4-hydroxymethamphetamine (pholedrine) with both reactions partially regulated by CYP2D6 (Lin et al., 1997), and (3) beta-hydroxylation to produce norephedrine