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In line, AC has shown antiproliferative effects on 4T1 breast cancer cells, with an IC 50 of 117 g/mL, and has induced apoptosis by upregulating the pro-apoptotic proteins Bax and caspase-3, while downregulating the anti-apoptotic Bcl-2 protein

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doi: 10.1016/j.jnutbio.2016.10.005 216

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