[DOI] [PMC free article] [PubMed] [Google Scholar] [15].Zorov DB, Juhaszova M, Sollott SJ, Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release
Resveratrol, an antioxidant, which is believed to increase sirtuin 1 expression, was able to delay onset of symptoms, prevent motor neuron loss and extend survival when treatment was initiated at early stages of the disease in hSOD1 G93A mice (Mancuso et al., 2014)
Exenatide improved mitochondrial function, reduced oxidative stress and prevented apoptosis in Wolfram syndrome iPSC-derived neural precursors and cerebellar neurons
Tc gi Siddharth Sonthalia (Ngy ng: Nm 2016)
The brain is susceptible to oxidative damage, and glutathione helps protect neurons and maintain healthy brain function
The SLR underpinning this study did not identify any formal sequencing studies or direct comparisons of SGLT2is versus GLP-1 RAs [16]