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Approximately 90% of participants in both groups also were taking riluzole, an approved ALS therapy sold as Rilutek, Tiglutik, and Exservan

For a once-weekly peptide like semaglutide where consistent dosing drives therapeutic response, these errors accumulate over the life of the vial

Response: We appreciate commenters' concerns that the proposed methodology for arriving at a value when the median, 10th percentile, or 90th percentile allowed amounts fall between two different values is not standard and may require additional programming or calculations by hospitals and this creates additional burden

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Vitamin C serves as a crucial cofactor for collagen synthesis

It helps maintain a healthy nervous system and is also involved in the production of red blood cells