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Weight change in the placebo group was 3.1% (95% CI, 4.3 to 1.9)

Limitations of This Comparison Several structural limitations constrain everything above, and honest readers should keep them in view: No head-to-head data

Increasing your dose before your body has acclimated increases the risk of side effects including nausea, vomiting, and GI discomfort

This change also reflects potential considerations regarding tolerability, clinical outcomes, and affordability

These medications are generally considered a long term, potentially lifelong treatment, as Yet, 32% of people who begin taking GLP-1 weight loss medications stop within a year due to several reasons, including the high cost and severity of side effects

Novo began selling its Wegovy injection at $349 a month to cash payers in November