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While researchers arent exactly sure the cause, they postulate that it is a result of gut dysbiosis or disruption of the normal gut flora

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Di Cesare Mannelli L, Ghelardini C, Toscano A, Pacini A, Bartolini A (2010) The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain

Adjustments to the treatment plan can be made based on these readings