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3.2.3.2 Spatiotemporal regulation of hypoxia signals Hypoxia differentially regulates ferroptosis and ICD through the HIF signaling pathway
Implications & Mechanisms The fact that Reta slowed tumor growth without causing weight loss suggests it may act through: Direct effects on tumor cells and/or Modulation of immune responses or metabolism inside the tumor microenvironment
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Potential applications of amino acid metabolism regulation in the diagnosis and treatment of IPF Amino acids as emerging biomarkers in IPF Although traditional biomarkers such as KL-6, SP-D, MMP-7, TIMPs, and CCL18 remain commonly used in IPF diagnosis and monitoring [130], emerging evidence suggests that amino acid metabolic profiles may offer valuable diagnostic and prognostic insights
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