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However, a study challenged the butyrate deficiency theory by identifying higher fecal concentrations of butyrate, isovalerate, and valerate in ME/CFS specimens, linked to increased bacterial fermentation

[3] Patients should not self-adjust their supplementation regimen without guidance from their GP or bariatric team

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Originally developed as an anti-obesity drug candidate in the late 1990s, it has since found research applications in both metabolic studies and cartilage repair investigations

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