If acute anal fissures, or tears around the anus, are not treated quickly, they could turn into chronic fissures
This timing rationale is also discussed in relation to dosing frequency and peptide clearance in BPC-157 TB-500 Half-Life: Why Daily Dosing Beats Weekly
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Knudsen PB, Hanna B, Ohl S, Sellner L, Zenz T, Dohner H, et al
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Testing for vitamin B12 or folate deficiency is not routinely included in blood work ordered at an annual physical exam