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At 10 nmol/l Ex-4 inhibits IB-phosphorylation and prevents NF-B/p65 nuclear translocation, halving tumor necrosis factor alpha (TNF-) and IL-6 both intracellularly and in the medium [19], thereby attenuating pro-inflammatory signaling and enhancing hMSC viability under inflammatory conditions

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People living with HIV often experience accelerated biological aging, even when the virus is well controlled with modern antiretroviral therapy, explained first author Michael Corley, PhD, an associate professor at the UC San Diego School of Medicine and the Stein Institute for Research on Aging

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