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doi: 10.1038/nature15524 82 LaoJ.ChenM.YanS.GongH.WenZ.YongY.et al

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Phase 2: Cagrilintide introduction (weeks 9-16) Once retatrutide at 2 mg is well-tolerated, introduce cagrilintide at the lowest dose

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Although we did not assess the estrous phase, it is speculated that hormonal fluctuations in females may have interacted with or masked memory deficits

In experimental settings, it is explored for its influence on circadian rhythms, cortisol modulation, and central nervous system balance