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Aggrecan molecules link to hyaluronic acid forming massive aggregates trapping water
Standard sterile injection technique applies for any subcutaneous administration
The entry site for glenohumeral injection, however, is a little lower, and the direction different
The PEN form is a technical choice, not a different molecule: the ready solution eliminates reconstitution and improves the repeatability of draws from a constant mg/ml concentration, in exchange for greater sensitivity to storage conditions and a shorter stability window after opening