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GHK Cu is a synthetic coppertripeptide complex composed of glycyl L histidyl L lysine (GHK) chelated with copper(II), used in research to study tissue remodeling, extracellular matrix regulation, and copper dependent signaling in vitro and in animal models

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doi: 10.1016/S1734-1140(13)71069-7 35 ErdogduNathansonDSjholmNystrmTZhangQ

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A large number of bioactive molecules can be cleaved by DPP-4 in vitro , but only a few of these have been demonstrated to be physiological substrates

The risk of bias in each study was assessed using the Cochrane Collaboration tool [17]