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Classically, GLP1Rs are categorized as G_s protein-coupled receptors (GPCRs), which activate the production of cyclic adenosine monophosphate (cAMP), a crucial secondary messenger mediating numerous physiological responses

Kindel TL, Wang AY, Wadhwa A, Schulman AR, Sharaiha RZ, Kroh M, et al

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Therefore, ferroptosis and various tumor microenviroment-related molecules may co-occur during the development and treatment of RCC, and further understanding of the interactions, core targets, and related drugs of ferroptosis may provide new combination drug strategies for RCC treatment