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The experimental trail included a 26-week treatment period, a dose-escalation period of up to 6 weeks, and a 6-week follow-up period after the end of treatment

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doi: 10.1177/0300060520964024 51 YangHZhengJ

Yes, Contrave can cause an increase in blood pressure and heart rate, which is why it should not be used by people with uncontrolled hypertension

It is worth noting that both GSSG and H 2 O 2 concentrations significantly decrease over time to 0 M