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The initial rapid and short-lived release facilitated by Large Dense Core Vesicles (LDCVs) at the plasma membrane is followed by a sustained release of insulin that depends on the mobilization of insulin-secreting granules (ISGs) to the plasma membrane for exocytosis 1

10.1161/01.RES.0000262653.84850.8b 384

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These studies have provided important clues to understand the mechanism of action of carnitine in different pathological states and laid the foundation for the development of new therapeutic strategies

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Antioxidants of natural plant origins: from sources to food industry applications