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For instance, an inverse relationship was described between the chlorambucil effect and GSH levels and activity [119,120] or between GSH levels and the concentration of cyclophosphamide active metabolites, suggesting a possible decrease in their efficacy during anticancer treatments [121]

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The two clusters expressed lipid related genes, but exhibited the low Lpl expression, which distinguished them from other LAMs that were mainly associated with fibrosis or inflammation

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