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10.1016/j.brainres.2018.09.012 Brain Res

Stool softeners such as docusate sodium (Colace) have minimal evidence supporting their efficacy as monotherapy and are generally not recommended alone for semaglutide-induced constipation

In patients experiencing acute MI, elevated blood levels of carnitine were noted compared to healthy controls, likely due to impaired uptake or increased leakage from ischemic myocardium

Also, during STEP 5, a study to assess efficacy of semaglutide with a follow-up of 2 years, there is a post-hoc analysis that demonstrates a better performance in the self-reported Control of Eating Questionnaire(CoEQ) to measure changes in appetite versus placebo, with lower cravings for dairy and starchy foods and less desire for salty and spicy food at short-term (20 weeks) but also as a maintenance therapy at weeks 52 and 104 (178)

Not documented as a side effect in the available literature or clinical reports

doi: 10.1111/jgh.14642 140 ChenYZhangPChenWChenG