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Its simultaneous agonism at the GIP, GLP-1, and glucagon receptors positions it as a compound of active scientific interest in metabolic signaling and weight loss research

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At the same time, more of your existing NAD+ gets consumed by enzymes like CD38 and PARPs, which are activated by things like inflammation, oxidative stress, and DNA damage

Chronic: Excess intracellular sodium causes vascular hypertrophy, which increases vascular resistance and response to vasoconstriction and, in turn, increases BP