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The ability of the decreased CYP2E1 to suppress APAP-induced hepatotoxicity was previously reported by CYP2E1 knockout mice, indicating that CYP2E1 is the key enzyme responsible for the metabolic conversion of APAP into the active hepatotoxic NAPQI

24 mM/l NaHCO

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Although GhGPX9 and GhGPX10 (consisted of ~233 amino acids) were clustered in clade I along with GhGPX6, 8, 12, which each had about 166170 amino acids