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In girls with TS, p53 signaling was associated with carriage of the G allele of the rs2069502 CDK4 SNP (including a +1.5-fold increase in MDM2 expression, implying a repression of P53 function, 27 and a +1.5-fold increase in ATM expression, implying that DNA damage increased activation of P53

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In streptozotocin-induced type 1 diabetes mellitus mice, the BBB injury areas are mainly frontal cortex, occipital cortex, parietal cortex, thalamus, and midbrain [1]

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