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According to figures released by Worldpanel by Numerator, 6.3% of households now include at least one user, with uptake seeing steep year-on-year climbs (2.3% in 2024 and 4.1% in 2025)

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"Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction"