APP-PS1 mice showed significant impairment of glymphatic clearance as indicated by normal paravascular movement but little influx into the interstitium (APP-PS1 vs
Cytokine and 25HC detection assay TNF and IL-6 levels in the medium supernatant and mice serum were assessed by using a specific ELISA kit (eBioscience, California, USA)
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10.1186/2046-2395-3-6 63 DaiW.XiaoY.TuY.XiaoF.LuY.QinY.et al (2021)
The Fenton Reaction: Free iron can be involved in the formation of free radicals by the superoxide-driven Fenton reaction, leading to glutathione depletion, oxidative stress, degradation of protein and nucleic acids, and lipid peroxidation
Vitamin B12 supports the nervous system by maintaining myelin, which is the protective coating around nerves