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In adult clinical trials for weight reduction, allergic reactions occurred in 16% (8/50) of WEGOVY-treated patients with anti-semaglutide antibodies and in 7% (114/1,659) of WEGOVY-treated patients who did not develop anti-semaglutide antibodies [see Clinical Pharmacology (12.6)]

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While the findings of this study are not conclusive, the author did note that the reason more women than men may be experiencing acne when using Ozempic and similar medications is most likely due to hormonal differences between the two genders