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10.1056/NEJMoa1603827 [DOI] [PMC free article] [PubMed] [Google Scholar] 101.Pratley RE, Aroda VR, Lingvay I, Ludemann J, Andreassen C, Navarria A, et al

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Regular monitoring by a healthcare provider can help detect and manage any potential deficiencies before they lead to anemia

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This slows gastric emptying, increases satiety, and improves insulin sensitivity a powerful trifecta for weight management

However, indirect effects matter more: semaglutide reduces gastric motility and increases acid exposure time in your stomach, which amplifies ibuprofen's irritant potential