Vitamin B12 is integral to the synthesis of DNA, necessary for cell division and the creation of new cells
Blocks NNMT in fat cells In 3T3-L1 mouse fat cells, 30 M of 5-Amino-1MQ for 24 hours strongly lowered 1-MNA levels direct proof of NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)
The following are the most common signs of a deficiency
This approach identifies people who actually need it while avoiding unnecessary supplements and costs for others
When NNMT activity is dialed down, it allows for increased levels of nicotinamide adenine dinucleotide (NAD+), a coenzyme absolutely critical for countless metabolic processes, including energy production and cellular repair
What to avoid if you are allergic to cobalt