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Hair loss (telogen effluvium) associated with GLP-1 medications is primarily caused by rapid weight loss and caloric deficit rather than the medication itself
Injection site redness or irritation may occur and is usually manageable
Essential supplies Semaglutide 5mg vials (quantity based on your planned protocol duration) Bacteriostatic water (30ml vial provides enough for multiple reconstitutions) U-100 insulin syringes (1ml/100-unit for standard use, 0.5ml/50-unit for low-dose precision) Alcohol swabs (isopropyl alcohol pads for sterilizing vial stoppers and injection sites) Sharps container (for safe needle disposal) Aluminum foil (for light protection during storage) Labels (date of reconstitution, concentration, expiration) Recommended tracking tools Keeping accurate records transforms a guessing game into a data-driven protocol
Volume and Scale Large National Providers: High patient volume Negotiating power with pharmacies Technology investments pay off Can offer lower prices: $349-$499/month Small Regional Providers: Lower volume Less negotiating leverage Higher per-patient costs Often higher pricing: $499-$699/month Scale advantages allow larger providers to offer better pricing

This slow titration helps your body adjust and minimises side effects: 6 Weeks 1-4: 0.25 mg once weekly Weeks 5-8: 0.5 mg once weekly Weeks 9-12: 1.0 mg once weekly Weeks 13-16: 1.7 mg once weekly Week 17 onwards: 2.4 mg once weekly (maintenance dose) Practical tips for taking both medications Inject Wegovy on the same day each week, at any time of day, with or without food Continue taking metformin with meals as prescribed Stay well hydrated, especially if experiencing gastrointestinal side effects Eat smaller, more frequent meals if nausea is troublesome Limit ultra-processed food and take-aways Who should not combine Wegovy and metformin