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Aging appears to follow a predictable biological pattern at both the cellular and systemic levels

In triple-negative breast cancer, curcumin is noted to reinstate the expression of the tumor suppressor DLC1 by restricting the oncogene Enhancer of zeste homolog 2 (EZH2) through the reduction of Histone 3 lysine 27 trimethylation (H3K27me3) enrichment in the DLC1 promoter, consequently inhibiting the proliferation, migration, and invasion of TNBC cells while achieving apoptosis (Zhou X

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In support of this notion, indirect calorimetry revealed an increase in the respiratory exchange ratio (RER) of p53 KO mice during the refeeding phase (Fig

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