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While mild to moderate cases can be managed with non-invasive treatments, severe spinal stenosis often requires surgery

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Quick answer In the REDEFINE trials CagriSema is given once weekly by subcutaneous injection, with both components titrated in parallel from 0.25 mg + 0.25 mg up to a 2.4 mg + 2.4 mg weekly target

Continued advancement of the understanding of HIC separation mechanism and increased availability of commercial columns will lead to wider applications of HIC, for example on lysinelinked ADCs, which have yet to be explored

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