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Remarkably, there is evidence that GLP-1 agonists can enhance left ventricular ejection fraction, inotropy, coronary blood flow, cardiac output, and vascular endothelial function because of their cardiovascular effects and decrease overall cardiovascular event risks

doi: 10.1038/ncpendmet0621 116 SedelnikovaOARedonCEDickeyJSNakamuraAJGeorgakilasAGBonnerWM

Not everyone requires or benefits equally from this treatment

Moreover, supplementation with EPA and DHA has been shown to modulate nociceptive responses, potentially through activating the opioid system, offering benefits in neuropathic pain scenarios

Genetic counseling (hereditary neuropathy): CMT is autosomal dominant (CMT1A/1B) or X-linked (CMTX) in most cases

10.3389/fphys.2018.01561 64 TesarikJ.Galn-LzaroM.Mendoza-TesarikR