Sheppard J, Shen Lee B, Periman LM
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Providers often recommend slower titration schedules, lower starting doses, or extended intervals between dose increases to allow physiological adaptation and permit early identification of adverse effects
Phase 2 Trials: Obesity A landmark phase 2 trial, published in The New England Journal of Medicine on June 26, 2023, evaluated retatrutides efficacy and safety in 338 adults with obesity (BMI 30 kg/m or 2730 kg/m with weight-related conditions, excluding T2D)
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