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FOXP3 is a transcription factor essential for the development and function of CD4 + CD25 + Treg cells

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In addition, the amino groups of arginine and lysine bind with carbonyl groups of carbohydrate can also produce advanced glycation end products, such as glucosepane, pentosidine, and hydroimidazolone [22]

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Fumarate Fumarate is another example of an oncometabolite produced by the action of fumarate hydratase on succinate