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What does the actual research show about GLP-1 medications and mental health

This would establish Wegovy, and possibly other potent anti-obesity therapies, as a backbone of CV risk management, with far-reaching implications beyond a change in clinical practice

What the Research Actually Shows Published research on AOD-9604 describes: Modest body fat reduction in preclinical and early clinical settings Reduced triglycerides in some studies Minimal effect on IGF-1 confirmed across the clinical dataset Good tolerability adverse event rates in the phase 2 obesity trials were comparable to placebo Variable weight loss some patients respond better than others, consistent with many metabolic interventions The effect size in phase 2 obesity trials was modest typically in the range of a few pounds over the study period

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LncRNA SRA deregulation contributes to the development of atherosclerosis by causing dysfunction of endothelial cells through repressing the expression of adipose triglyceride lipase

Colley WC, et al