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The core mechanism lies in synergistically promoting anabolic processes while inhibiting catabolic processes, thereby jointly maintaining cartilage homeostasis

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Lifestyle factors like exercise, caloric moderation, and adequate sleep can support NAD production to some degree

Moreover, it is required for the transport and metabolism of fats and cholesterol within the body, an important function for the support of the endocrine, cardiovascular, and hepatic systems

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Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms Nature Reviews Gastroenterology and Hepatology 2022;19(10):625-637 doi:10.1038/s41575-022-00631-9 (Review) Written by Ali Rza Akn Microbiome Scientist, Author & Founder of Next-Microbiome Ali Rza Akn is a microbiome scientist with nearly 30 years of experience in translational biotechnology, systems biology, and applied microbiome research, spanning discovery, preclinical development, and clinical-stage translation