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This knowledge aims to support the use of A1AT in therapeutic applications

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Long-term NMN administration rescues the age-associated decline in physiological function, including mitochondrial function, energy metabolism, gene expression changes, insulin sensitivity and plasma lipid profile, thereby improving physical activities, such as bone density and eye function

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doi: 10.3390/molecules28186620 33

Peptides as a drug class are sometimes described as having fewer off-target effects than small-molecule drugs because of their target specificity, and FDA guidance reflects this general principle