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Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival

The peptide acts as a signaling molecule, influencing gene expression i n approximately 31% of the hum an genome, promoting tissue regeneration, collagen synthesis , and antioxidant protection.

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In a mouse AKI model, knockdown of FTH1 aggravated RM- and cisplatin-induced renal injury, suggesting that FTH1 may play a protective role against ferroptosis in the context of AKI [160, 161]