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Cross Talk proposal: 5-HT is necessary for peristalsis
PloS One 11 (5), e0156362
Given the robustness of this mitochondrial response, the multifaceted nature of PGC1 regulation in cells and a modest rescue at best by mTORC1 inhibition, we suspect that there is a degree of functional redundancy built into this metabolic plasticity system that can contribute to such an adaptive response, and complete inhibition of this system will prove difficult
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The peptides mechanism targets beta-3 adrenergic receptors, which are particularly concentrated in abdominal and visceral fat
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